Alix Spiegel

In this episode of Invisibilia, NPR's new show about human behavior, we wanted to explore entanglements: the invisible ways we're entangled with each other. So we called a comedian.

I'm a fan of Maria Bamford, who has done impressions of her mother throughout her career:

Fear is one of the strongest and most basic of human emotions, and it's the focus of Fearless, the second episode of Invisibilia, NPR's new show on the invisible forces that shape human behavior.

This segment of the show explores how a man decided to conquer his fear of rejection by getting rejected every day — on purpose.

The evolution of Jason Comely, a freelance IT guy from Cambridge, Ontario, began one sad night several years ago.

It's a tradition as old as New Year's: making resolutions. We will not smoke, or sojourn with the bucket of mint chocolate chip. In fact, we will resist sweets generally, including the bowl of M&M's that our co-worker has helpfully positioned on the aisle corner of his desk. There will be exercise, and the learning of a new language.

It is resolved.

So what does science know about translating our resolve into actual changes in behavior? The answer to this question brings us — strangely enough — to a story about heroin use in Vietnam.

One Friday night, 30 men and 30 women gathered at a hotel restaurant in Washington, D.C. Their goal was love, or maybe sex, or maybe some combination of the two. They were there for speed dating.

The women sat at separate numbered tables while the men moved down the line, and for two solid hours they did a rotation, making small talk with people they did not know, one after another, in three-minute increments.

The modern idea of stress began on a rooftop in Canada, with a handful of rats freezing in the winter wind.

This was 1936 and by that point the owner of the rats, an endocrinologist named Hans Selye, had become expert at making rats suffer for science.

"He would subject them to extreme temperatures, make them go hungry for long periods, or make them exercise a lot," the medical historian Mark Jackson says. "Then what he would do is kill the rats and look at their organs."

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